Battle of Churubusco - Mexican-American War - Winfield Scott

Skirmish of Churubusco - Mexican-American War - Winfield Scott Skirmish of Churubusco - Conflict Date: The Battle of Churubusco was battled August 20, 1847, during the Mexican-American War (1846-1848). Armed forces Commanders US Significant General Winfield ScottMajor General William J. Worth8,497 Mexico General Manuel RinconGeneral Pedro Anaya3,800 Skirmish of Churubusco - Background: With the start of the Mexican-American War in May 1946, Brigadier General Zachary Taylor won fast triumphs in Texas at Palo Alto and Resaca de la Palma. Delaying to fortify, he later attacked northern Mexico and caught the city of Monterrey. In spite of the fact that satisfied with Taylors achievement, President James K. Polk was progressively worried about the commanders political yearnings. Subsequently, and reports that a development on Mexico City from Monterrey would be troublesome, he started stripping Taylors armed force of men to shape another order for Major General Winfield Scott. This new armed force was entrusted with catching the port of Veracruz before moving inland against the Mexican capital. Polks approach about brought calamity when a severely dwarfed Taylor was assaulted at Buena Vista in February 1847. In urgent battling, he had the option to hold off the Mexicans. Arriving at Veracruz in March 1847, Scott caught the city following a twenty-day attack. Worried about yellow fever along the coast, he immediately started walking inland and was before long gone up against by a Mexican armed force drove by General Antonio Lopez de Santa Anna. Assaulting the Mexicans at Cerro Gordo on April 18, he steered the foe before progressing to catch Puebla. Continuing the crusade toward the beginning of August, Scott chose for approach Mexico City from the south as opposed to constrain the adversary protections at El Pe㠱ã ³n. Adjusting Lakes Chalco and Xochimilco his men showed up at San Augustin on August 18. Having foreseen an American development from the east, Santa Anna started redeploying his military toward the south and expected a line along the Churubusco River (Map). Skirmish of Churubusco - Situation Before Contreras: To guard the southern ways to deal with the city, Santa Anna sent soldiers under General Francisco Perez at Coyoacan with powers drove by General Nicholas Bravo toward the east at Churubusco. In the west, the Mexican right was held General Gabriel Valencias Army of the North at San Angel. Having set up his new position, Santa Anna was isolated from the Americans by an immense magma field known as the Pedregal. On August 18 Scott coordinated Major General William J. Worth to take his division along the immediate street to Mexico City. Walking along the east edge of the Pedregal, the division and going with dragoons went under substantial fire at San Antonio, only south of Churubusco. Incapable to flank the adversary because of the Pedregal toward the west and water toward the east, Worth chosen to stop. In the west, Valencia, a political opponent of Santa Anna, chose for advance his men five miles south to a situation close to the towns of Contreras and Padierna. Looking to break the stop, Scott sent one of his designers, Major Robert E. Lee, to discover a way through the Pedregal toward the west. Effective, Lee started driving American soldiers from Major Generals David Twiggs and Gideon Pillows divisions over the harsh territory on August 19. Over the span of this development, an ordnance duel initiated with Valencia. As this proceeded, American soldiers moved unnoticed toward the north and west and took positions around San Geronimo before dusk. Clash of Churubusco - The Mexican Withdrawal: Assaulting around sunrise, American powers broke Valencias order at the Battle of Contreras. Understanding that the triumph had unhinged the Mexican barriers in the region, Scott gave a progression of requests following Valencias rout. Among these were orders which reversed before mandates for Worths and Major General John Quitmans divisions to move west. Rather, these were requested north towards San Antonio. Sending troops west into the Pedregal, Worth immediately outmaneuvered the Mexican position and sent them reeling north. With his position south of the Churubusco River falling, Santa Anna settled on the choice to start pulling back towards Mexico City. To do as such, it was important that his powers hold the scaffold at Churubusco. Order of the Mexican powers at Churubusco tumbled to General Manuel Rincon who guided his soldiers to involve fortresses close to the scaffold just as the San Mateo Convent toward the southwest. Among the protectors were individuals from the San Patricio Battalion which comprised of Irish weaklings from the American armed force. With the two wings of his military joining on Churubusco, Scott promptly requested Worth and Pillow to assault the extension while Twiggs division ambushed the religious community. In a strange move, Scott had not explored both of these positions and was unconscious of their quality. While these assaults pushed ahead, the detachments of Brigadier Generals James Shields and Franklin Pierce were to move north over the extension at Coyoacan before turning east for Portales. Had Scott surveyed Churubusco, he undoubtedly would have sent the greater part of his men along Shields course. Clash of Churubusco - A Bloody Victory: Pushing ahead, the underlying ambushes against the extension bombed as Mexican powers held. They were helped by the opportune appearance of local army fortifications. Restoring the ambush, the detachments of Brigadier Generals Newman S. Clarke and George Cadwalader at long last conveyed the situation after a decided assault. Toward the north, Shields effectively crossed the stream before meeting a predominant Mexican power at Portales. Under tension, he was strengthened by the Mounted Rifles and an organization of dragoons which were taken from Twiggs division. With the scaffold taken, American powers had the option to decrease the religious circle. Charging forward, Captain Edmund B. Alexander drove the third Infantry in raging its dividers. The religious circle immediately fell and a large number of the enduring San Patricios were caught. At Portales, Shields started to pick up the high ground and the adversary started to withdraw as Worths division was seen progressing from extens ion toward the south. Clash of Churubusco - Aftermath: Joining together, the Americans mounted an insufficient quest for the Mexicans as they fled towards Mexico city. Their endeavors were hampered by the restricted highways which crossed damp territory. The battling at Churubusco cost Scott 139 slaughtered, 865 injured, and 40 missing. Mexican misfortunes numbered 263 slaughtered, 460 injured, 1,261 caught, and 20 missing. A grievous day for Santa Anna, August 20 saw his powers vanquished at Contreras and Churubusco and his whole cautious line south of the city broke. With an end goal to purchase time to rearrange, Santa Anna mentioned short détente which Scott conceded. It was Scotts trust that harmony could be haggled without his military raging the city. This ceasefire immediately fizzled and Scott continued activities toward the beginning of September. These saw him win an expensive triumph at Molino del Rey before effectively taking Mexico City on September 13 after the Battle of Chapultepec. Chosen Sources PBS: Battle of ChurubuscoSon of the South: Battle of Churubusco Aztec Club: Battle of Churubusco - Map

Case Study Drugs affecting the Upper Gastrointestinal Tract

Question: Portray about the Case Study for Drugs influencing the Upper Gastrointestinal Tract? Answer: 1. Mrs. Johnson is taking the medication since she is experiencing the gastroesophageal reflux malady (GERD). Metoclopramide is a medication for essentially stomach and oesophageal sicknesses. It helps in the compression in the upper bit of the stomach related tract. It additionally diminishes acid reflux brought about by GERD. So she is being treated with the medication. 2. The significant patient factors here are acid reflux, and the reactions of the medication Metoclopramide that she is taking like queasiness, restlessness and tension. 3. Attendant can assist with advancing treatment by observing pharmacodynamic markers. With an adaptable way to deal with medication and dose choice, it should be conceivable to oversee GERD in a powerful way. 4. The patient is having acid reflux that isn't serious. Quiet has indicated symptom towards the drug Metoclopramide. Quiet has demonstrated restlessness, sickness, and tension. Since persistent demonstrated symptoms towards the medicine and the acid reflux type isn't not kidding the patients case. The patient can take acid neutralizers since they can stop the indigestion and treat rapidly to the side effects of GERD. The patient additionally can get treatment of Histamine type 2 receptor foes. This treatment can make the stomach produce less acids. What's more, will bring down the acid reflux. The patient can likewise get treated by proton siphon inhibitors. That can likewise diminish the warmth consume. The patient ought to follow an adjustment in way of life. 5. Since the patient has indicated reactions for the medications she may take stomach settling agents for a brisk help and with almost no base symptoms. The symptoms for H2RA s might be a migraine, clogging, sickness. PPIs can show reactions like a torment in the midsection, heaving, queasiness, and looseness of the bowels. PPIs can build the opportunity of getting contaminations inside digestive system or lungs.PPI s can likewise expand the inclination of breaking a bone. 6. To amplify the remedial impacts it is must significant that the patient ought to follow to keep up a solid way of life, a sound eating regimen, do standard exercise, taking legitimate rest and quit liquor. The patient ought to abstain from eating nourishments that may build her acid reflux or difficult to process. Additionally the patient should take appropriate meds or different choices, for example, acid neutralizers, 7. The patient ought to experience the treatments appropriately under the management of the medical caretaker. Stay away from nourishments that can build the disease. The patient ought to abstain from eating any food before hitting the hay. The patient ought to stop liquor to get the advantage of the treatment. The patient ought to experience the treatment that has insignificant symptoms. 8. The patient should treat appropriately for her consistent acid refluxes. On the off chance that that stay unchecked, at that point she may get into genuine medical problems. She ought to maintain a strategic distance from the eating nourishments that may trigger indigestions. She ought to follow a solid way of life and abstain from drinking liquor during treatment. The accompanying tests, for example, Endoscopy, oesophageal pH checking and manometry of the patient could help better in the treatment procedure. The test oesophageal pH observing can assist with seeing whether the patient requires careful treatment or not.

I Lost My Mom to COPD - Donnas Story

I Lost My Mom to COPD - Donnas Story Addiction Nicotine Use Smoking-Related Diseases Print I Lost My Mother to COPD COPD Stole My Mothers Life By Terry Martin facebook twitter Terry Martin quit smoking after 26 years and is now an advocate for those seeking freedom from nicotine addiction. Learn about our editorial policy Terry Martin Updated on June 24, 2019 altrendo images/stockbyte/Getty Images More in Addiction Nicotine Use Smoking-Related Diseases After You Quit How to Quit Smoking Nicotine Withdrawal The Inside of Cigarettes Alcohol Use Addictive Behaviors Drug Use Coping and Recovery A Life Lost to COPD In part one of this story, Donna, a member of the Verywell.com Smoking Cessation support forum shared the tragic story of  how smoking-related lung cancer took her fathers life. Just a few short months later, Donna and her family were confronted with another smoking-related death in the family.  This time it was their  mother who died of  COPD, even though she never smoked (directly) a day in her life. It is more than likely that living in a smoking home for years upon years was a major influence in the development of the COPD that eventually killed Donnas mother. Thank you for sharing your very personal story with us here Donna. Smoking-related disease is the most preventable cause in the world today, and I know your account will make a difference to every person who reads it. From Donna: My mother passed away on Thursday, January 14, at 1:30 pm. I was blessed to be there when she passed. My sister called me on Wednesday, and asked me to stay with her and Mom until the time came. I didnt think twice...I hopped into my vehicle and drove the hour north to my parents place. My mothers condition had steadily worsened in the last week, and even Hospice nurses marveled over my mothers will to live over the last few days. She was no doubt in agony, and each breath was taken at the result of great personal pain. There are some end-of-life symptoms which are inherent to kidney failure, but those of COPD are unmistakable...My mother gasped and twisted her head for each tortured breath. During the last two days, when she sank into a coma, the Hospice nurse took her oxygen tube and placed it in her open mouth. She had lost the ability to breathe through her nose. The Hospice nurse looked at us and said, It could be tonight or tomorrow. Im almost tempted to stay here, Im fairly certain shell go tonight. We told her we would be okay, and she reluctantly left. I spent the night there. My sister slept in a recliner next to the hospital bed, and I lay on a twin mattress on the floor in the room. I spent the night wavering between a restless sleep and groggy wakefulness, when I would look at the bed and watch my mom point her head as she struggled. Dreams tortured what snatches of sleep I stole. In one dream, my mother threw off the blankets, dropped the bed rails, and hung her thin legs over the side of the bed to look at me. You know, she chirped, I think Im going to get out of here today. She then looked around, and a cloud of uncertainty shifted over her features. She sighed, glared at her oxygen tube tether and said, Oh, never mind. I think Ill just stay in bed. And she lay back down again, covered herself, adjusted her oxygen tube, and resumed her comatose state. I awoke to see Moms prone, sleeping form, and I shivered. The dream had seemed so real. Dawn just couldnt come soon enough. As the day progressed, my mothers breaths became shallower and shallower, and the period of time between breaths longer and longer. Finally, after a long exhalation, no further breaths came. It was over. My sister went to the kitchen and lit a cigarette. I stood on the back porch, and with dry eyes felt my whole being start screaming. I have never felt so alone as I did the day my remaining parent passed away. I am now truly alone in the world. None of us can, with full certainty, determine when and how we will end our lives. My mother was no exception. She did not choose to die of COPD, nor did she choose to smoke...Her death from a smoking-related disease was from secondhand smoke from my father. Through this incredible sorrow in my heart, Im at least comforted that she is no longer suffering. She is no longer in agony. There ARE some things each of us can control. We can control whether or not we smoke a cigarette. We can control our exposure to others cigarette smoke. We can lobby our legislators for stricter laws regarding tobacco products, for laws that assure our right to clean air, and even start calling for an outright ban on tobacco. Please make no mistake, tobacco kills in horrific ways. I am 36 years old, and yesterday, I lost my parents within 10 months of one another, and they both died from tobacco. I have seen several posts at the Verywell .com Smoking Cessation support forum where new quitters have found, within the words here, the ability to stay quit for one more day. Please, please understand, what you fight isnt just an addiction. Its a certain death you are avoiding. By not smoking, you are reducing your risk of cancer, of COPD, of emphysema, of macular degeneration, of heart disease, of limited blood circulation...The list goes on and on and on. How Smoking Harms Us, From Head to Toe When I smoked, the biggest lie I told myself was that smoking-related diseases happen to other people. Well, those other people were the two people I loved most in this world. It was Daddy and Momma. Ive witnessed two deaths which will haunt me until my own time comes. My saving grace in quitting were these forums, and the people who had quit before me, and the people who quit with me. In a very real sense, I owe my life to Terry and the moderators and the members here. Without them, I would not have quit. Had I not quit, the horrific deaths of my parents would very much be my own death. And so, I have changed my destiny. I ask you to do the same. I challenge you to NOT take the chance to be that other person. Please, if you are thinking of lighting up again tonight, dont do it. Use the resources here. Fight your way through your quit. Cherish those clean breaths, protect them, and love those you are with for everything you are worth. Dont torture your loved ones with a death like Ive described in this message. Break free of nicotine addiction, and change your destiny, too. Youll never regret it once you get to the other side. I promise. ~Donna If youre still smoking please use the resources below to get a head start on your quit program. Your Quit Smoking Toolbox The Support Forum at Verywell.com Smoking Cessation Quit smoking now.

Economics Classical Economics And Keynesian Economics

As interesting as the subject of economics is, it’s a subject that isn’t easily understood. In order to grasp the subject you have to really understand the concepts. And it’s not like riding a bike, once you know how to do it you will always have it engraved in your head. I will attempt to highlight the key factors of the two theories of economics: classical economics and Keynesian economics. Since Classical Economics is considered to be the first school of economics. I will start to explain this concept first. In the 18th and 19th centuries, there was a group of economists that worked together to develop theories to explain how market to market relationship work between each other. The most important contributor to the classical school of economics was the great economist Adam smith, whom is considered the founder. Adam Smith stated in an excerpt from ‘An Inquiry into The Nature and Causes of The Wealth of Nations’. â€Å"By pursing his own interest, he (man) frequently promotes that (good) of the society more effectively than when he really intends to promote it. I (Adam Smith) have never known much good done by those who affected to trade for the public good.† You will understand that from those thoughts Adam Smith created the foundation of classical economics. It is key to point out the basic structure or assumptions that form classical economics. The three theories that sticks out to me are: Say’s Law: Say’s law suggests that aggregate production in an economy generatesShow MoreRelatedClassical Economics And Keynesian Economics1124 Words   |  5 Pagesof Classical Economics and Keynesian Economics has given me the opportunity to form an opinion on this greatly debated topic in economics. After researching this topic in great lengths, I have determined the Keynesian Economics far exceeds greatness for America compared to that of Classical Economics. I will begin my paper by first addressing my understanding of both economic theories, I will then compare and contrast both theories, and end my paper with my opinions on why I believe Keynesian EconomicsRead MoreClassical Economics And Keynesian Economics1898 Words   |  8 PagesModern Economics is divisible into two identifiable schools of thought: Classical Economics and Ke ynesian Economics. Names such as Adam Smith, Thomas Malthus, Jean-Baptiste Say, among several others are commonly associated with Classical economic thinking; meanwhile, one ‘key’ name associated with the Keynesian model is, as its title suggests, John Maynard Keynes. The goal of each of the two schools of thought is to predict the state of an economy and the appropriate responses of a few chief partiesRead MoreClassical Vs Keynesian Economics1235 Words   |  5 PagesClassical and Keynesian economics are both accepted schools of thought in economics, but each had a different approach to defining economics. The Classical economic theory was developed by Adam Smith while Keynesian theory was developed by John Maynard Keynes. Similarities: One of the most surprising similarities between the two theories is that John Keynes developed his theory based on the Adam Smith’s theory. Keynes did not entirely disagree with Adam Smith but rather, expanded the theory basedRead MoreMacroeconomic Theories Of Macroeconomics And Classical Economics999 Words   |  4 PagesMacroeconomics is a branch of economics dealing with the performance, structure, behavior, and decision-making of an economy as a whole, rather than individual markets. This includes national, regional, and global economies. With microeconomics, macroeconomics is one of the two most general fields in economics. There are two major macroeconomic theories that economists use to describe the economy. Those theories are Keynesian and Classical. Each theory has a different approach to the economic study of monetaryRead MoreThe Theory Of The Classical School1694 Words   |  7 Pages The classical school is one of the economic thoughts; the key assumption of this school is that the market system is the most efficient system in the sense that the unencumbered market mechanism ensures the optimal allocation and utilisation of scarce resources. They also believed that â€Å"Supply creates its own demand.† (The early debate on policy atavism) In other words, in the process of producing output, businesses would also create enough income to ensure that all of the output will be sold.Read MoreEconomic Studies: Quantitative and Qualitative Analysis793 Words   |  3 PagesEconomics studies many different things such as how governments, firms, individuals, and nations make decisions on distributing limited assets to fulfill their unlimited wants. It is broken down into two categories, macroeconomics, and microeconomics. Macroeconomics focuses on the behavior of the economy while microeconomics focuses on and individual as a consumer. Economics also focuses on two different studies known as quantitative and qualitative analysis in which they focus on the distributionRead MoreEconomic Advisement Paper1634 Words   |  7 PagesOption 1: Economic Advisement Paper Brittany McCarty, Jake Vickers, amp; Michelle Williams Learning Team B Eco 372 July 11, 2013 Dr. Samuel Imarhiagbe Two Economic Theories Modernizing over the decades, two main theories support economists, proposals, arguments, and predictions. The first theory is the Classical model perspective and the second theory is the Keynesian model perspective. The first theory promotes a hands-off approach and the second a governmentRead MorePolicy Review And The Lucas Criticisms Essay919 Words   |  4 Pages Policy Review and the Lucas Critiques Orthodox Keynesian economists believe that the change of the money supply will lead to the change of effective demand, and further result in the change of the economy. However, in the monetary economy cycle theories, the expected monetary supply changes will not influence the total economy; the unexpected money supply changes will impact the total economic in short term. In the long term, it merely impacts the changes of general price levels, instead of onRead MoreEssay on Keynesian Revolution1244 Words   |  5 PagesKeynesian Revolution Classical economic theory assumed that a ‘free-market’ economy is a ‘self regulating’ system that continually tends toward a full-employment equilibrium, with optimum economic benefits for everyone. Therefore, the best government economic policy is to ‘excuse itself’ and give utmost freedom to individual enterprise. A key element of the ‘Keynesian revolution’ was its demonstration that these basic assumptions are false, both in theory and practice, and its assertionRead MoreIntroduction. The Rising Unemployment Has Generated Challenges1381 Words   |  6 Pagesimpacts on the communities and economic growth of the country. The prevalence of high unemployment rates in low income communities in the U.S contributes to increased poverty rates, leads to development of social unrest and conflicts, and hinders effective flow of liquidity thus limiting labor mobility (Phelps Zoega, 2002). This paper seeks to study on the effects of the rising unemployment in low income communities using the theories of economics. Theories of Economics Explaining the Effects of Rising

Comparing Beowulf, The Anglo Saxon And Beowulf s Motivations

Beowulf, the Anglo Saxon Epitome: An analysis of the Anglo Saxon code and Beowulf’s Motivations The story of Beowulf is an outstanding example of the Anglo Saxon code. But what is the Anglo Saxon code? What is a code? A code is something to live by, often an unwritten pledge and standard to live by as one resides or partakes in a team with unity. Code is defined simply as â€Å"program instructions.† For instance, if one participates in a school sport activity, such as cross country, there is an unwritten code that each participant needs to be nothing but positive, that each athlete, no matter how good or bad, contributes to the team in some way, and that each athlete gives their full effort even if it doesn’t measure up to the effort†¦show more content†¦Initially, the anglo saxon code is injected into the Beowulf epic poem in that Beowulf greets King Hrothgar with respect, therefore making Beowulf a character who displays the unwritten law of respecting elders. An example of this is shown when Beowulf enters Hrothgar’s palace and greets him, year ning to defeat Grendel, the enemy of the Danes, who the king and his soldiers cannot defeat: â€Å"Hail, Hrothgar! Higlac is my cousin and my king; the days Of my youth have been filled with glory. Now Grendel’s Name has echoed in our land: sailors Have brought us stories of Herot, the best of all mead-halls.† Beowulf is immediately respectful of his elder Hrothgar, as he basically demeans the power of Hrothgar and his community in that they need help from an outsider with great might. Beowulf is a mighty warrior and could very easily overtake Hrothgar’s throne, and though Beowulf is aware of this, he is careful to identify himself as lower class to Hrothgar because Hrothgar is a king, and Beowulf is not. This is a direct instance of the anglo saxon code being portrayed in this epic poem, the idea that the young

Problem of Induction An Analysis of the Validity of the Humean Problem of Induction Free Essays

Induction refers to â€Å"a method of reasoning by which a general law or principle is inferred from observed particular instances† (Flew, 1986, p. 171). The method of inductive inference, in this sense, may be considered as the primary means through which justifications are formulated to show the relationship of evidence towards particular assumptions (Goodman, 1983, p. We will write a custom essay sample on Problem of Induction: An Analysis of the Validity of the Humean Problem of Induction or any similar topic only for you Order Now 13). The process of induction, thereby, may be seen as arising whenever we note that evidence lends support to a hypothesis while in the process failing to establish its deductive certainty. In relation to the aforementioned method, Hume argued that since no necessary connections exists between empirical phenomena, it is always possible that a future observation will prove our inferences wrong no matter how appealing it may have been or how richly supported by past observations. This problem has been referred to as the problem of the uniformity principle [in this sense the lack of such uniformity]. According to the argument, nature has no uniformity. If such is the case, it thereby follows that there is no voucher that ensures the consistency of man’s most refined predictions. Consider for example, the statement â€Å"Whenever I drop a piece of chalk it will fall†. Two claims may be inferred from such a statement: (1) Dropping a piece of chalk causes it to fall and (2) Dropping a piece of chalk tomorrow will thereby cause it to fall. According to Hume, such claims assume the uniformity of nature. The problem however is evident if one considers that if all knowledge of causation is based on experience and all knowledge of experience is based on the faculties of cognition, in order for knowledge of causation to be valid [at all times] it is necessary that the faculties of cognition are infallible. However, such is not the case since conditions for the attainment of understanding are based upon fallible faculties. If such is the case, it follows that man’s understanding of the empirical world is obscure thereby providing no solid grounds for the formation of inferences that determine the uniformity of nature from which man derives his causal laws regarding the workings of nature. At this point, it is worthwhile to consider that the aforementioned problem [commonly referred to as Hume’s problem of induction] stems from Hume’s critique of the Cartesian claims regarding the powers of reason. According to Descartes, man is in possession of an infallible faculty of clear and distinct perception which if properly exercised is able to grasp various general causal principles a priori. In addition to this, Descartes claims that possession of such faculties enables man to establish the essence of the mind [which is thinking] and the body [which is extension] through the use of pure intellectual insight. If such is the case, man is thereby privy to the acquisition of a priori knowledge regarding the behavior of minds and of things. If such is the case, it follows that man is also privy to the knowledge of the workings of the external world [external to the mind and hence the physical realm]. As was noted at the onset of this paper, Hume’s critique of Descartes’ conception of the powers of reason has thereby resulted to the critique of the process of induction and hence the critique of the assumption regarding the uniformity of nature. It is important to note that Hume’s claim [as an opposition to Descartes’ aforementioned claim] may be understood in two ways. In the first case, Hume’s claim may be understood as setting the limits of man’s intellectual capacities [which is evident in his emphasis on the fallibility of our faculties for cognition]. In another sense, one may understand Hume’s claim as enabling a naturalistic conception of knowledge acquisition thereby enabling the dissolution of Descartes’ dualism [evident in Descartes’ distinction of the mind from the body]. The importance of such lies in its emphasis on the necessity to set solid foundations for the acquisition of belief. Within these grounds, it is thereby possible to understand Hume’s subtitle to A Treatise of Human Nature, which states, â€Å"Being an Attempt to Introduce the Experimental Method of Reasoning into Moral Subjects†. Hume’s naturalized epistemology may thereby be seen as an attempt to enable the provision of valid and indubitable grounds for the formation of beliefs within both the empirical and moral realms of human existence. How to cite Problem of Induction: An Analysis of the Validity of the Humean Problem of Induction, Papers

IT on Everyday Life

Introduction The information revolution was sparked in the mid 20th century, when scientists built the first programmable electronic computers. Since then, the growth of IT has become a major and significant aspect of people in their daily lives. Today, many people depend on IT either directly or indirectly. This paper critically examines how IT aspects affect our daily lives as employees, students, family members and community membersAdvertising We will write a custom essay sample on IT on Everyday Life specifically for you for only $16.05 $11/page Learn More Discussion IT and Human Survival Since IT was invented and taken to the public domain, it has become a major aspect of human survival in the world, especially in the developed world (Michael 2009). Many people have become too dependent on IT as a means of life, and this has made IT a major human need in many areas of the world. As William (2011) asserts, one way that IT has become an important comp onent of human survival is by providing efficient and cheap communication. Information has been a very important aspect of human survival for as long as human beings have existed. The communication of this information is therefore very important for individuals and communities. Today, this communication is in terms of money transfer, information sharing on social networks, and accessing official information from government agencies through online platforms such as online portals. Internet has also made it very possible for people to access jobs that are miles away from their location. Impact of E-commerce According to Mathew (2010), electronic commerce has made it possible for businesses in one area to be able to access markets that are many kilometres from their geographical locations. A good example of businesses that have been able to use e-commerce to take advantage of markets far away is Amazon, which is one of the oldest online businesses. The advantages of e-commerce are not only oriented to the businesses only, but also to the consumers (Wesley 2011). Consumers are able to easily buy directly from manufacturers, who are geographically very far from them and this means that the consumers of a product that is not produced locally, are able to enjoy the product that is produced elsewhere. Social computing As Maxwell (2009) notes, social computing has become a very easy way for people to socialize. While there are many negative things that have been attributed to social computing such as internet addiction and deterioration of real social life, social life can also be seen as a positive way for people to socialize and reach out.Advertising Looking for essay on computer science? Let's see if we can help you! Get your first paper with 15% OFF Learn More This is especially important for people who are physically disabled, since they can still meet their friends on social networks and virtual chartrooms. Research shows that many people who have l ost self esteem and are unable to freely socialize with people in the real world are able to get their esteem back if they have a social media they use, because it is easier for them to express themselves on the cyber sphere (Gerald 2009). Future of social computing The future of social computing can only be seen from a speculative point of view (Danileson 2009). There are those who believe that as time goes, more people who are unable to cope in the real world, will go online and start having virtual lives. This will therefore start affecting even those who are not deep into the virtual online world. These people argue that in future, social computing will become more acceptable and the cyber sphere will help all people live more enhanced lives. On the other hand, some argue that social computing will get out of hand and affect people negatively, by making it impossible for important social developments to occur or for people to make meaningful relationships. IT and efficiency Info rmation Technology has definitely increased efficiency in many ways in people’s lives. One thing that has benefited from IT to gain efficiency is money transfer. With the help of information technology, money transfer has been made much easier and simpler, and processes that used to take days or even weeks to complete, can today be completed in a matter of hours or minutes. Communication has also become easier and cheaper as a result of developments in IT. This can be found within organizations where networks have been used to increase efficiency in the way information is shared among various departments. Databases have brought about a new way to manage and retrieve information efficiently. Engineers now don’t have to go through the heavy tasks of designing models on paper using a pencil and thousands of lines. Computer Aided Design is a software-based way for such engineers to easily and efficiency produce, modify and redesign models of whatever things they are design ing, such engines, airplanes, vehicles and buildings.Advertising We will write a custom essay sample on IT on Everyday Life specifically for you for only $16.05 $11/page Learn More IT becoming a necessity Information Technology has changed how the world works, and individuals don’t have a choice, but to acquaint themselves with the technology. Computers have become a necessity, because to access much important information such as that from government agencies, they have to use computers. Without a computer and an internet connection, it has become very difficult for individuals to live. Most government agencies have continually moved their services into the cyber sphere and for individuals to access these services, they have to be conversant with IT. IT and student works Modern IT systems have made student work easier and better. Students are able to access a lot of information online for their research. As James (2009) points out, assignments ca n now be better researched online in the pre-IT times, unlike earlier, when the library was the only source of information. Today, with millions of web servers on the internet, including journals, blogs, electronic encyclopedia and other forms of information, a student can access information to enrich his or her assignment. With a computer, a student can produce a neat document using word processors such as MS word, and either submit this document in an electronic format or print it out using a printer. These IT systems such as computers, softwares, printers and photocopiers, have not only made the work of the student better, but also easier to manage, thus making it possible for them to produce high quality works. Disadvantages With the advent of these IT systems, it is easier for students to cheat in their work, because the students can easily copy information directly from the internet, instead of reading and synthesizing the information in order to produce their own work. As a r esult, these IT systems can also be seen as hindrances to the development of education and the quality of education that the students will gain from school. The other disadvantage of these systems is that they are only accessible if one has an internet connection and therefore, may not be useful if there is no internet connection.Advertising Looking for essay on computer science? Let's see if we can help you! Get your first paper with 15% OFF Learn More Conclusion Information Technology will continue to be a major contributor to human survival. Scientists argue that by the year 2035, IT singularity will have occurred, which means that computers and humans will be able to interact at a physiological level, and that the computers will be more intelligent than human beings. Whether that is or is not possible remains to be seen. However, the fact that IT has been a major contributor to human existence is not debatable. References Danileson, K 2009, â€Å"The Way Forward for Social Media,† Forum for Informaitron Technology and Socail Change, vol. 3 no. 7, pp. 29-31. Gerald, K 2009, â€Å"Understanding the Social Impact of Tecnology,† International Institute of Techology Review, vol. 5 no. 5, pp. 45-46. James, L 2009, â€Å"How IT is changing the Lives of Ordinary People in the World,† Journal of Technology, vol. 4 no. 5, pp. 45-48. Mathew, K 2010, â€Å"Modern Business and the Role of Information Technology,† Journal of Economics, vol. 3 no. 4, pp. 29-23. Maxwell, J 2009, â€Å"Modern Infroamtion Systems,† Journal of Infroamitron Technology, vol. 4 no. 7, pp. 12-13. Michael, K 2009, â€Å"Understanding Modern IT Sytems,† Journal of computing Technology, vol. 4 no. 8, pp. 29-31. Wesley, K 2011, â€Å"Ecommerce and Infromaiton Technology,† Journal of Economics, vol. 3 no. 8, pp. 34-36. William, E 2011, â€Å"Understanding Modern Information Interchange,† Journal of computing Technology, vol. 4 no. 7, pp. 67-69. This essay on IT on Everyday Life was written and submitted by user Rafael Vega to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Goiter essays

Goiter essays A goiter is often referred to as an enlargement of the thyroid gland which is not caused by inflammation or cancer. Goiter, when at a simple level, occurs when the thyroid gland can not produce enough of the thyroid hormone to meet the bodys daily requirements. As a counteraction, the thyroid gland enlarges, which usually overcomes small thyroid hormone deficiencies. A simple case like this is called either an endemic goiter or a sporadic goiter. Endemic goiters often occur within groups of people living in areas with soil with low iodine, usually regions away from the sea coast. Most people in these communities might not get enough iodine in their diet which is important for the production of the thyroid hormone. Use of iodized table salt in the U.S. prevents this; however it is still common in central Asia and central Africa. Another cause for goiter is use of the medications lithium and aminoglutethimide, used to treat some kinds of tumors that affect the adrenal cortex. Some cases of goiter are caused by hereditary factors, Most of the causes for goiter, however, are unknown to us at this time. Risk factors for the development of a goiter include female sex, age over 40 years, inadequate dietary intake of iodine, residence in an endemic area, and a family history of goiter. Goiter may be prevented by avoiding use of the medications shown above, and the use of iodized table salt, as indicated above. A few of the symptoms of goiter include any sort of thyroid enlargement, breathing difficulties due to compression of the trachea, swallowing difficulties due to the compression of the esophagus, and dizziness when arms are raised above the level of the head. There are many tests that may determine if you have goiter or not. Some of these including measurements of thyroid stimulating hormone and thyroxine in the bloodstream, a thyroid scan, and finally an ultrasound on the thyroid. ...

Past Simple Verb Form Example Worksheets

Past Simple Verb Form Example Worksheets The past simple takes the following forms: Past Simple Positive: Subject past simple form of verb objects Jason went to camp in Florida last week.We had dinner at that new restaurant two days ago. Past Simple Negative Form: Subject did not verb objects Mary didnt attend the meeting last week.They didnt pass the exam yesterday. Past Simple Question Form: (Question Word) did subject verb? What did you do yesterday?When did they meet Tim? Important Notes ï » ¿The verb to be does not take the auxiliary verb did in the question or negative form.The regular past simple form of verbs ends in -ed, irregular past simple form of verbs vary and must be studied. Examples I was on time to the meeting yesterday.Alexander wasnt born in April. He was born in May.Were you at the party last night? Ago / Last / In Ago is used at the end of a sentence preceded by a specific amount of time such as: three days ago, two weeks ago, one month ago, etc.Last is used with week, month, and year.In is used with specific months and years in the past. Practice Worksheet 1 Conjugate the verb in parentheses using the form indicated. In the case of questions, use the indicated subject as well. Tom _____ (visit) his mother last weekend.We _____ (not buy) that TV yesterday because it was too expensive._____ (you / be) at the meeting on Tuesday?Where _____ (Sheila / stay) in New Orleans?Alan _____ (understand) the situation two days ago.They _____ (not finish) the project on time last month.When _____ (Mary / fly) to New York?Henry _____ (read) Harry Smiths latest book last month.I _____ (not write) that letter to him last week.What _____ (you do) yesterday afternoon?You _____ (think) he couldnt win, didnt you?She _____ (not win) the prize two weeks ago.Where _____ (Andy / go) last week?Thomas _____ (come) to visit us in May.Susan _____ (not telephone) in time to get a ticket.How _____ (you meet) him?David _____ (get up) early on Saturday to play golf.Betty _____ (not draw) that picture._____ (Peter forget) his books yesterday?She _____ (give) him a present for his birthday yesterday. Practice Worksheet 2 Choose the correct time expression used with the past simple tense. Cathy left on holiday (last / ago) week.I played football (when / last) I was in high school.Were you able to go to the meeting (ago / in) May?She didnt think about those problems two days (last / ago).There werent any children at the party (last / when) Saturday.Jennifer wanted us to come and help three weeks (ago / when).Peter went to a meeting in Chicago (last / ago) Tuesday.Alexander made a number of mistakes (yesterday / tomorrow).Tom was born (at / in) 1987.Our teacher helped us understand the problem (this morning / tomorrow morning).I bought a new chair for my office (last / next) week.Did you finish the meeting on time (yesterday / last) evening?Susan visited her aunt in Seattle (last / ago) Sunday.My father took me to the zoo (when / last) I was a child.They opened a new store (in / on) Tuesday.She drove to New Mexico (in / on) February.We enjoyed a lunch with our friends (yesterday / tomorrow).Annabelle played the piano for two hours (on / in) Tuesday.Fred didnt attend the meeting (last / ago) week. Anne opened a bottle of wine two hours (ago / last). Worksheet 1 Answers Tom visited his mother last weekend.We didnt buy that TV yesterday because it was too expensive.Were you at the meeting on Tuesday?Where did Sheila stay in New Orleans?Alan understood the situation two days ago.They didnt finish the project on time last month.When did Mary fly to New York?Henry read Harry Smiths latest book last month.I didnt write that letter to him last week.What did you do yesterday afternoon?You thought he couldnt win, didnt you?She didnt win the prize two weeks ago.Where did Andy go last week?Thomas came to visit us in May.Susan didnt telephone in time to get a ticket.How did you meet him?David got up early on Saturday to play golf.Betty didnt draw that picture.Did Peter forget his books yesterday?She gave him a present for his birthday yesterday. Worksheet 2 Answers Cathy left on holiday last week.I played football when I was in high school.Were you able to go to the meeting in May?She didnt think about those problems two days ago.There werent any children at the party last Saturday.Jennifer wanted us to come and help three weeks ago.Peter went to a meeting in Chicago last Tuesday.Alexander made a number of mistakes yesterday.Tom was born in 1987.Our teacher helped us understand the problem this morning.I bought a new chair for my office last week.Did you finish the meeting on time yesterday evening?Susan visited her aunt in Seattle last Sunday.My father took me to the zoo when I was a child.They opened a new store on Tuesday.She drove to New Mexico in February.We enjoyed a lunch with our friends yesterday.Annabelle played the piano for two hours on Tuesday.Fred didnt attend the meeting last week.Anne opened a bottle of wine two hours ago.

Critique of a Qualitative Research Paper Essay Example | Topics and Well Written Essays - 2250 words

Critique of a Qualitative Research Paper - Essay Example In addition, the researchers have particularly concentrated upon the social marketing, which looks for striving for the betterment of society at large. Social marketing, Andreasen (1995:31) submits, is the application of commercial marketing technologies to the analysis, planning, execution, and evaluation of programs designed to influence the voluntary behavior of target audiences in order to improve their personal welfare and that of their society. In other words, the main objective of the social marketing is working voluntarily for the benefit and uplift of the individuals at large. Moreover, it is also a reality that the young people are the future builders of a society, proper education and training of which is one of the most formidable responsibilities of all members of asocial set up. If the youth is not discouraged and prohibited from participating into the social evils including drinking, smoking and gambling etc, the future prospects of the society would be in grave jeopar dy for the future years of come. In addition, it has aptly been observed that gambling leads the young people towards other nefarious activities including drinking and sex etc, which may challenge their health condition. Hence the social problem, selected by the researchers, is very important in its scope and exposure, and carries wide scope and depth in its nature. The researchers are quite justified in choosing the research problem related to social marketing, which looks to strive for the wellbeing and safety of the young people on the basis of the findings of the study, as well as the suggestions made on the foundations of the findings of the present research. Whether positively or negatively the gambling prevention campaigns, being launched by the government and non-governmental organizations at various media platforms, influence the minds of the young

Hazard of your choice Lab Report Example | Topics and Well Written Essays - 1000 words

Hazard of your choice - Lab Report Example While the centre of the storm is the calmest with light winds, the further parts of the storm are very violent. When this comes to land, it leads to heavy rains, large waves and strong winds that can damage property, land, buildings, trees, cars and result into heavy flooding leading to loss of animals and human life. The magnitudes of the impacts of hurricanes can be understood from the meteorologists â€Å"Saffir-Simpson Hurricane Wind Scale.† In this scale, the magnitude of hurricane is categorized in a scale of 1-5, however, this scale do not address the impacts of such magnitudes. According to Kislow (21), category one consists of winds ranging from 74-95 mph and result into minor damages to property, falling debris, limited flying and minor injuries to people and animals. Category 2 consists of winds ranging from 96 to 110 which have potential to result into heavy property damage. According to Kislow (21), this category of hurricanes consist of winds with high velocities which carry debris thus poses threat to animals, humans and significant damage to apartment buildings, mobile homes, shopping centers and result into extensive power outages. Category 3 consists of heavy winds of approximately 111 to 130 mph and can result into extensive property damage. This category of hurricane has potential of destroying even well built homes, cause extensive inland flooding and damage to electricity and water sources and lines. Category 4 hurricane consists of winds ranging from 131 to 155 mph and can cause serious catastrophic damage to humans, property and animals. As stated by Vecchi et al (5341), it can cause significant catastrophic damage to apartments, frame homes, as well as shopping centers and include long term water shortages and power outages of up to few months. Category five consists of winds that ranges from 131 to 155 mph and can course complete destruction to property, apartments, trees, shopping malls, and land. It is also important

Effect of Medicinal Plant Extracts on Alzheimers Disease

Effect of Medicinal Plant Extracts on Alzheimers Disease Alzheimer’s disease (AD) is a neurodegenerative disease which causes a lethal twist in the structural integrity, and a roadblock in the function of brain, this eventually channel the situation to degeneration and shrinkage of brain, and override the control of brain over other parts of the body, and comes to the final closing remark of the disease- death. Studies done on the topic have corroborated that the disease is not reversible, and the only patch of hope is slowing down its progress. But as the disease advances through mid stage and evolves into severe AD, the condition of patient becomes pathetic and care giving becomes more painful. Studies have reported that notable symptoms of AD are seen only after 60 years of age, even though the disease has started before that. Initial symptoms are loss of short term memory- being forgetful about the recent events, and gradually over a period of time patient seems more absent –minded about the environment, things which are chemically etched in the long term memory begins to be erased, and the final stage starts pushing the patient into severe AD which is tremendously pathetic. Studies have proved that loss of function of neurons is the cause of AD. A closer look into the aspect revealed a complex set of events that precede the neuronal degeneration- oxidative stress and imbalance in homeostasis, formation of roadblocks in communication, falling apart of integrity and death of neurons. This enabled to go beyond the findings of superficial studies done and hypothesis developed, and helped to delve much deeper into the inner workings and mechanism of the disease. Hypotheses developed to explain mechanism of AD are: amyloid cascade hypothesis, cholinergic hypothesis and tau hypothesis. Amyloid cascade hypothesis says, APP- Amyloid Precursor Protein, a transmembrane protein involved in main roles of growth, survival and repair of nerve cells- is snipped at wrong places by an enzyme called secretase, leading to the formation of amyloid ÃŽ ² peptides which accumulates to form plaques- amyloid plaques- and bind to synapses blocking the communication channel, event ually causes memory loss. According to cholinergic hypothesis, downward drift in the levels of acetylcholine in brain is the cause for Alzheimer’s disease. Loss of function of cholinergic neurons was found in Alzheimer’s disease patients. Shift in the level of acetylcholine happens due to the lack of two enzymes involved in synthesis and breaking down of acetylcholine. This will lead to loss of function of neurons; brain’s functionality falls apart, and eventually leads to symptoms of Alzheimer’s disease. Tau hypothesis approaches the problem in another perspective, tau protein- a protein associated with microtubules in nerve cells- gets hyperphosphorylated, this enables cross linking among tau protein units, and they back off from being attached to the microtubules. This causes loss of structural integrity of nerve cells, and they collapse and clump to form tangles- neurofibrillary tangles. Studies conducted focusing on the inner workings of these hypoth esis have found that oxidative stress is the reason that enhances plaque and tangle formation, repair mechanisms in cells are unable to solve the situation as the oligomer formation and cross linking are predominantly made by non peptide bonds. In another study, amyloid ÃŽ ² peptides have shown close relation with some causes of mad cow disease. Studies related to genetics of AD have found the link between APOE gene on chromosome 21 and the disease. APOE gene codes for apolipoprotein, and one among its functions is breaking down of APP. APOE has variants, APOEÃŽ µ4 is the one which codes for less active protein whose capacity to break down APP is sluggish. People with this variant gene are more tend to develop AD in later stages of life, and any abnormality related to chromosome 21 also results in AD over a period of time. To know more about the mechanism of disease and its attachment to oxidative stress, further studies have done from different angles, and all the studies have come to a common point, the findings from all the studies stitched together gave a complex and elaborate picture about the mechanism of the disease. Free radical damage leads to oxidation of products in cell. Oxidation leads to new end products of glycation, nitration, lipid peroxidation, and oxidation of nucleic acids. These new end products chemically modify other proteins and compartments inside the cell. Oxidized derivatives impede with the channel of trace elements, and imbalances their homeostasis, and enables proteins like tau to form non peptide cross linking. In response to changes cell up the levels of heme oxygenase-1 (HO-1)- an antioxidant enzyme to mitigate the bad effects from free radical damage- but rapid heaping up of neurotoxic substances goes beyond control leading to severe imbalances, blockage of communicati on channels, and eventually death of neuron. Since mitochondria is the main source of free radicals and oxidative precursors. Certain deletions in mtDNA resulted in change in normal levels and rates of metabolism and production of free radicals. Free radicals formed in mitochondria are short lived and they do not have the ability to cross membrane and reach cytoplasm to cause damage, this led studies in a new direction and found free radicals- OH from cytoplasm- can attack guanidine in RNAs in cytoplasm and this both can cross the membrane and reach into mitochondria, and cause imbalance and production of more stable H2O2 radicals which can come to cytoplasm and react with the channel of trace elements, and starts the primary events for the major causes for AD to come into being. AD starts at neocortex area of brain, and as the neurons die and rupture, the neurotoxic substances- plaques, free radicals, tangles, etc. pervade the nearby nerve cells, and the cycle goes on and graduall y covers the brain and makes it slip out of its normal being. Oxidative stress in brain leads to degeneration of neurons, which eventually leads to dementia, and Alzheimer’s disease (AD). This oxidative stress in brain can be slowed down or reversed- to a small extent- using drugs to treat AD or using antioxidant capacity of some medicinal plants. In this study rats were arranged into seven groups, and different groups were treated with different plant extracts and rivastigmine. AD was induced using aluminum chloride- rats were given aluminum chloride for one month, and the dosage was 17mg/kg of body weight. One group was kept as control- healthy control and another group as AD-induced. Rivastigmine was given to group 3. Group 4 and 5 were treated with extracts of a medicinal plant- Salvia triloba; and group 6 and 7 were treated with extract made from Piper nigrum. The rats were given drug and extracts for three months. At the end of three months duration biochemical assays and histopathology was done to examine the changes happened to t he brains. The following things were checked for in serum: malondialdehyde, total antioxidant capacity and nitric oxide, and level of superoxide dismutase were checked in erythrocytes. Acetylcholine and acetylcholine esterase levels were checked in brain samples and another group of brain samples were given for histopathology. From the results, the rats which were treated with Piper nigrum extract and rivastigmine showed increase in brain Ach, and serum TAC and SOD; and a significant decrease in brain AchE, and serum MDA and NO. The rats which were treated with extract of Salvia triloba showed even better result in subduing the oxidative stress to a certain limit. Antioxidant capacity of plants was used to bring down the effects of oxidative stress in brain. Here, the effect of the extract made from Boswellia serrata is compared with rivastigmine on rats with AD- induced by oral administration of aluminum chloride. Ninety male rats were used in the study. They were made into nine groups. Group 1 was kept as healthy control, group 2 was given with aluminum chloride for four weeks, and group 3 was treated with rivastigmine, group 4 and 5 were treated with two different concentrations of plant extract made from Boswellia serrata. Groups 3 to 5 were treated with a combination of aluminum chloride and other things to check the ability of extract and drugs to protect the brain from the stress. Group 6 was given with water after inducing AD. Group 7 was given with rivastigmine, and group 8 and 9 were given with two different concentrations of plant extract- this was done for twelve weeks. Cognitive tests were done at the beginning of each new stage o f the study. At the end of the duration of the study, the brain samples were subjected to biochemical assays and histopathology. From the results, B.serrata has significant ability to reduce the oxidative stress in brain, and higher dose if the extract showed better effect- bringing down the severity of oxidative stress damage. Bacopa monnieri is another plant used to trim the effects of AD. This plant is used since ancient times for improving intelligence, and in this study its ability to protect against AD is checked. Alcoholic extracts of the plant was made for the study. AD was induced using ethylcholine aziridinium ion (AF64A)- administered intracerebroventricular way bilaterally. Plant extract was given to the rats two weeks before and one week after the administration of AF64A. rats were subjected to cognitive tests. Rats treated with the plant extract cleared the tests in less time. Histopathology results showed, low dose of the plant extract brought down the degree of damage in brain- reduction of neurons density. Low dose showed better result compared to the medium and high dose. The study has not revealed the mechanism of action of the plant extract, but it showed the scope for a further study on the same. Targeted drug delivery to brain in case of Alzheimer’s disease is more complex process due to many factors like blood brain barrier and actions of plasma proteins. But nanoparticles are used for targeted drug delivery, and this is again affected by physiochemical properties of Nanoparticles in different surfactants, stability of nanoparticles and organic coating or capping agent on nanoparticles. Blood brain barrier is a homeostatic defense mechanism used by brain to screen out pathogens and unwanted materials from entering brain. The barrier screens the solutes biochemically, physicochemically and structurally at the periphery. There are times when blood brain barrier breaks down due to certain infections or due to any physical reason, and this makes it skew from its usual nature- highly selectively permeable. Studies have been conducted to find how nanoparticles are treated at blood brain barrier. In a study, nanoparticles were made by warm microemulsion precursors, and the nanoparticles were radiolabelled by entrapment. Then an in situ study was conducted to check how nanoparticles cross the blood brain barrier. From the study it was concluded that endocytosis or transcytosis as possible mechanism for the transport across the barrier- more studies are yet to be conducted. Studies have shown that clioquinol- a quinoline derivative- can solubilize amyloid ÃŽ ² plaques in vitro and this could prevent accumulation of amyloid ÃŽ ² plaques in Alzheimer’s disease transgenic mice- an in vivo study. Clioquinol has shown its ability to dissolve plaques which are induced by Zn and Cu ions- NMR studies have shown that clioquinol can remove bound Cu ions from amyloid ÃŽ ² plaques. The study conducted has overlooked the toxicity part of clioquinol- though clioquinol has many side effects attached to it at high doses. It has shown in the later part of the study that clioquinol coupled with nanoparticles could easily cross the blood brain barrier- higher degre e of uptake by brain. So, clioquinol-nanoparticle delivery system is suggested to be considered as one among the models for treating Alzheimer’s disease by targeted drug delivery. Even though using nanoparticles are considered for drug delivery, there are studies showing the side effects, and doses. In a study- toxicity of silver nanoparticles- it was found that exposure to more than 125mg/kg of silver nanoparticles will lead to liver damage due to toxicity. In a study curcumin nanoparticle formulation was used to test its effect on Alzheimer’s disease in mice. Nanocurcumin was synthesized and orally given to the mice for twelve days. Memory tests were done before starting every new stage of the experiment. Results have shown that mice treated with nanocurcumin could clear the cognitive tests- significant improvements were observed.

How to Address Conflicts or Dilemmas Essay

1.1Describe potential conflicts or dilemmas that may arise between the duty of care and an individual`s rights. In our care work we mostly work with children and young people who may not have the ability to judge what is good for them and what is not. In those cases it is our responsibility and job as individuals and as a team to provide them what we judge is best for them. In some other cases they have the skills to get involved in the decisions and this can lead to conflicts and dilemmas. Potential conflicts between the service user and the care worker in our job role can arise from disagreeing in certain questions e.g. what is healthy to eat, what is not, what is more important when having a meal: quality or quantity, what activities or forms of entertainment (films, songs, etc.) are age-appropriate and/or mentally and emotionally adequate and so on. 1.2Describe how to manage risks associated with conflicts or dilemmas between an individual`s rights and the duty of care. If a conflict arises, I can never force a learner to do or not to do things unless the law or the School Policy allows me to (for example if they want to watch an age-inappropriate film, but in these cases I always have to refer to my line manager). What I can do if a conflict in these questions arises between me and the learner is to provide all the information about the risk carried by their decisions in a supportive, encouraging way, and then let them make their own choices. Every time when a conflict arises I should record what actions were taken to provide every source for the learner to make their own decision and what choice they made. I always should seek for advice at my line manager.

The Case of the Floundering Expatriate - A Case Analysis...

INTRODUCTION In an Economic Times article on the 15th of September there is a report that says that more and more expatriates and foreign corporate managers are queuing to take up Indian assignments. This is because the idea of an Indian experience from a growth and role perspective offers them a huge value addition. As an HR head says India is a market of constant learning and provides expatriates with a foundation for a global tomorrow. This article if taken in context with the case in question gives us the clear correlation between foreign assignments and future corporate success. A foreign assignment with all its hardship and adjustment fears is a perfect platform for future CEO s to showcase their abilities. Success in a foreign†¦show more content†¦His wife is bored without work; their eldest daughter is facing problems with grades in the British school. The problem is not just a temporary adjustment problem. Donaldson is at his wit s end as he has tried everything possible to appease and motivate his staff but they refuse to listen. The problem is so serious that Bert has personally admitted to his inability to handle the juniors. Frank has to take a decision with regard to Donaldson. Some of the options include sticking with him for another year, firing him or sending him back to America. ANALYSIS OF THE TWO MAIN CHARACTERS Donaldson His stint in Europe is marked by numerous cultural faux pas due to his lack of cultural savvy. He does not interact with his juniors, learn Swiss German, and is unpunctual too. His schedules run overtime, he does not know how to show adequate respect to his subordinates. The incident with Hassler epitomizes what is wrong with Bert. Even when he tries to be at his best behaviour he is unable to communicate with the vice president. Frank Waterhouse Frank s desire to rise to the top at any cost becomes detrimental to his company as he refuses to see the problem as his own. Frank failed to usher in Donaldson. This can be seen by the fact that he did not even attend the first workshop. As CEO he also does not have any proper communication channels as the news of dissatisfaction with Bert reaches him very late. He is also excessively fearful of adverse reactions fromShow MoreRelatedUnited Arab of Emirates Country Notebook18844 Words   |  76 PagesEmirates Country Notebook Presented to Dr. Shahira El Alfy Prepared by: Mohamed Ibrahim Osama Mosher Ismail Ahmed El-Mohamady Hesham Mostafa Eslsca 36 – Global Management I. Cultural Analysis: Identification of the Emirates History: The United Arab Emirates (UAE) consists of the seven emirates, which are: Abu Dhabi, Dubai, Sharjah, Ras Al-Khaimah, Ajman, Umm Al-Qaiwain, and Fujairah. They were united as a federal state on 2Read MoreUnited Arab of Emirates Country Notebook18844 Words   |  76 PagesEmirates Country Notebook Presented to Dr. Shahira El Alfy Prepared by: Mohamed Ibrahim Osama Mosher Ismail Ahmed El-Mohamady Hesham Mostafa Eslsca 36 – Global Management I. Cultural Analysis: Identification of the Emirates History: The United Arab Emirates (UAE) consists of the seven emirates, which are: Abu Dhabi, Dubai, Sharjah, Ras Al-Khaimah, Ajman, Umm Al-Qaiwain, and Fujairah. They were united as a federal state on 2Read MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words   |  1573 Pagesaware of a trademark claim, the designations have been printed in initial caps or all caps. Library of Congress Cataloging-in-Publication Data Robbins, Stephen P. Organizational behavior / Stephen P. Robbins, Timothy A. Judge. — 15th ed. p. cm. Includes indexes. ISBN-13: 978-0-13-283487-2 ISBN-10: 0-13-283487-1 1. Organizational behavior. I. Judge, Tim. II. Title. HD58.7.R62 2012 658.3—dc23 2011038674 10 9 8 7 6 5 4 3 2 1 ISBN 10: 0-13-283487-1 ISBN 13: 978-0-13-283487-2 Brief Contents Preface

Can I Own a Gun in America

While gun owners and dealers often cite the Second Amendment to the U.S. Constitution when arguing against restricting any American citizen from owning a gun, the fact is that all gun owners and dealers must follow federal and state laws in order to legally own or sell guns. Since as early as 1837, federal gun control laws have evolved to regulate the sale, ownership, and manufacture of firearms, various firearm accessories, and ammunition. Highly Restricted Types of Firearms First, there are some types of guns most civilian Americans simply cannot legally own. The National Firearms Act of 1934 (NFA) greatly restricts the ownership or sale of machine guns (fully automatic rifles or pistols), short-barreled (sawed-off) shotguns, and silencers. Owners of these types of devices must undergo deep FBI background checks and register the weapon with the Bureau of Alcohol, Tobacco, Firearms, and Explosives NFA registry. In addition, some states, like California and New York, have enacted laws completely banning private citizens from possessing these NFA-regulated firearms or devices. Persons Restricted From Owning Guns The Gun Control Act of 1968, as amended by the 1994 Brady Handgun Violence Prevention Act, prohibits certain people from possessing a firearm. The possession of any firearm by one of these prohibited persons is a felony offense. It is also a felony for any person, including a registered Federal Firearms Licensee to sell or otherwise transfer any firearm to a person knowing or having reasonable cause to believe that the person receiving the firearm is prohibited from firearm possession. There are nine  categories of people prohibited from possessing firearms under the Gun Control Act: Persons under indictment for, or convicted of, any felony crime punishable by imprisonment for a term exceeding one yearFugitives from justicePersons who are unlawful users of, or addicted to, any controlled substancePersons who have been declared by a court as mental defectives or have been committed to a mental institutionIllegal aliens or aliens who were admitted to the United States under a nonimmigrant visaPersons who have been dishonorably discharged from the Armed ForcesPersons who have renounced their United States citizenshipPersons subject to certain types of restraining ordersPersons who have been convicted of a misdemeanor crime of domestic violence In addition, most persons under 18  years of age are prohibited from possessing handguns. These federal laws impose a life-long ban on gun possession by anyone convicted of a felony, as well as those merely under indictment for a felony. In addition, the federal courts have held that under the Gun Control Act, persons convicted of felonies are banned from owning guns even if they never serve jail time for the crime. Domestic Violence In cases involving an application of the Gun Control Act of 1968, the U.S. Supreme Court has rather broadly interpreted the term â€Å"domestic violence.† In a 2009 case, the Supreme Court ruled that the Gun Control Act applies to anyone convicted of any crime involving â€Å"physical force or the threatened use of a deadly weapon† against any person with whom the accused had a domestic relation, even if the crime would be prosecuted as simple â€Å"assault and battery† in the absence of a deadly weapon. State and Local ‘Right to Carry’ While the federal laws regarding the basic ownership of guns apply nationwide, many states have adopted their own laws regulating how legally-owned guns may be carried in public.   As in the case of fully automatic firearms and silencers, some states have enacted gun control laws that are either more or less restrictive than federal laws. Many of these state laws involve an individual’s â€Å"right to carry† handguns openly in public. In general, these so-called â€Å"open carry† laws, in the states that have them, fall into one of four categories: Permissive Open Carry States: People are allowed to carry their legally-owned guns openly and in public.Licensed Open Carry States: People are allowed to carry their legally-owned guns openly and in public only with a permit or license to do so.Anomalous Open Carry States: While openly carrying a gun may generally be legal under state law, local governments are allowed to enact more restrictive open-carry laws.Non-Permissive Open Carry States: State law allows persons to openly carry legally-owned guns only in limited circumstances, like while hunting, during target practice, or when legally carried for self-defense. According to the Law Center to Prevent Gun Violence,  31 states currently allow the open carrying of handguns without the necessity of a license or permit. However, some of those states require that guns carried in public must be unloaded. In 15 states, some form or license or permit is required to openly carry a handgun.   It is important to note that open carry gun laws have many exceptions. Even among those states that allow open carrying, most still prohibit open carrying in some specific locations such as schools, state-owned businesses, places where alcohol is served, and on public transportation, among many other locations. In addition, individual property owners and businesses are allowed to ban openly carried guns on their premises. Finally, some—but not all—states grant visitors to their states â€Å"reciprocity,† allowing them to follow the â€Å"right to carry† in effect in their home states.